丙利酮

化合物

丙利酮(英語:Prorenone,研发代号:SC-23133)是一种有机化合物,分子式为C23H30O3,属于甾体抗鹽皮質激素,是丙利酸内酯,从未上市销售[1]

丙利酮
臨床資料
其他名稱SC-23133; 3-(17β-Hydroxy-6β,7β-methylene-3-oxo-4-androsten-17α-yl)propionic acid γ-lactone
ATC碼
  • 未分配
识别信息
  • (1aS,5aR,5bS,7aS,8R,10aS,10bR,10cS)-5a,7a-Dimethyl-1,1a,3',4,4',5,5a,5b,6,7,7a,9,10,10a,10b,10c-hexadecahydro-3H,5'H-spiro[cyclopenta[a]cyclopropa[l]phenanthrene-8,2'-furan]-3,5'-dione
CAS号49848-04-6
PubChem CID
IUPHAR/BPS
ChemSpider
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C23H30O3
摩尔质量354.49 g·mol−1
3D模型(JSmol英语JSmol
  • O=C6O[C@@]5([C@@]3([C@H]([C@@H]2[C@H]4[C@@H](/C1=C/C(=O)CC[C@]1(C)[C@H]2CC3)C4)CC5)C)CC6
  • InChI=1S/C23H30O3/c1-21-7-3-13(24)11-18(21)14-12-15(14)20-16(21)4-8-22(2)17(20)5-9-23(22)10-6-19(25)26-23/h11,14-17,20H,3-10,12H2,1-2H3/t14-,15+,16-,17-,20+,21+,22-,23+/m0/s1
  • Key:RRHHMFQGHCFGMH-LAPLKBAYSA-N
丙利酸

参考文献

  1. ^ Claire M, Rafestin-Oblin ME, Michaud A, Roth-Meyer C, Corvol P. Mechanism of action of a new antialdosterone compound, prorenone. Endocrinology. April 1979, 104 (4): 1194–1200. PMID 436757. doi:10.1210/endo-104-4-1194.