丹叶大黄素
化合物
丹叶大黄素(英語:Rhapontigenin)是一种芪类有机化合物,分子式C15H14O4,存在于紫葛(学名:Vitis coignetiae)和闭苞买麻藤(学名:Gnetum cleistostachyum)中[1],能抑制人CYP1A1酶[2]。
丹叶大黄素 | |
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IUPAC名 5-[(E)-2-(3-Hydroxy-4-methoxyphenyl)ethen-1-yl]benzene-1,3-diol | |
别名 | Protigenin 3,3',5-trihydroxy-4'-methoxystilbene piceatannol 4'-methyl ether |
识别 | |
CAS号 | 500-65-2 ![]() |
PubChem | 5320954 |
ChemSpider | 4478875 |
SMILES |
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InChI |
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InChIKey | PHMHDRYYFAYWEG-NSCUHMNNSA-N |
性质 | |
化学式 | C15H14O4 |
摩尔质量 | 258.27 g/mol g·mol⁻¹ |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考文献
- ^ Stilbenes from Gnetum cleistostachyum. Yao Chun-Suo, Lin Mao, LIiu Xin and Wang Ying-Hong, Huaxue xuebao, 2003, volume 61, no 8, pages 1331-1334, INIST:15332136
- ^ Chun, YJ; Ryu, SY; Jeong, TC; Kim, MY. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.. Drug metabolism and disposition: the biological fate of chemicals. 2001-04, 29 (4 Pt 1): 389–93. PMID 11259321.