千层纸素A

化合物

千层纸素A(英語:Oroxylin A,也称为5,7-二羟基-6-甲氧基黄酮,5,7-Dihydroxy-6-methoxyflavone)是一种天然的O-甲基化黄酮类化合物,存在于黄芩(学名:Scutellaria baicalensis[1]美黄芩(学名:Scutellaria lateriflora[2][3]木蝴蝶(学名:Oroxylum indicum[4]等植物中。

Oroxylin A
Skeletal formula
Ball-and-stick model of oroxylin A
IUPAC名
5,7-Dihydroxy-6-methoxyflavone
别名 Baicalein 6-methyl ether
识别
CAS号 480-11-5  checkY
PubChem 5320315
ChemSpider 4478428
SMILES
 
  • COC1=C(C=C2C(=C1O)C(=O)C=C(O2)C3=CC=CC=C3)O
InChI
 
  • InChI=1S/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5- 3-2-4-6-9/h2-8,18-19H,1H3
InChIKey LKOJGSWUMISDOF-UHFFFAOYSA-N
ChEBI 61668
性质
化学式 C16H12O5
摩尔质量 284.26 g/mol g·mol⁻¹
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

参考文献

  1. ^ Li, Hua-Bin; Chen, Feng. Isolation and purification of baicalein, wogonin and oroxylin A from the medicinal plant Scutellaria baicalensis by high-speed counter-current chromatography. Journal of Chromatography A. 2005-05, 1074 (1-2): 107–110. doi:10.1016/j.chroma.2005.03.088. 
  2. ^ Li J, Ding Y, Li XC, Ferreira D, Khan S, Smillie T, Khan IA. Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora. J. Nat. Prod. 2009, 72 (6): 983–7. PMID 19555121. doi:10.1021/np900068t. 
  3. ^ Nishikawa K, et al. Phenolics in tissue cultures of Scutellaria (PDF). Natural Medicines. 1999, 53 (4): 209–13. 
  4. ^ The constitution of oroxylin-A, a yellow colouring matter from the root-bark of Oroxylum indicum, vent R. C. Shah, C. R. Mehta and T. S. Wheeler