梭菌蛋白酶

梭菌蛋白酶(英語:ClostripainEC 3.4.22.8,其它英文名有:clostridiopeptidase B, clostridium histolyticum proteinase B, alpha-clostridipain, clostridiopeptidase, Endoproteinase Arg-C)是一种从梭菌属溶组织梭状芽胞杆菌英语Clostridium histolyticumClostridium histolyticum)中分离出的蛋白酶,在精氨酸的羧基端水解肽键[1][2][3],最适反应pH为7.4~7.8。

梭菌蛋白酶
Clostripain
识别码
EC編號 3.4.22.8
CAS号 9028-00-6
数据库
IntEnz IntEnz浏览
BRENDA英语BRENDA BRENDA入口
ExPASy英语ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc英语MetaCyc 代谢路径
PRIAM英语PRIAM_enzyme-specific_profiles 概述
PDB RCSB PDB PDBj PDBe PDBsum

参考文献

  1. ^ Mitchell, W.M. Cleavage at arginine residues by clostripain. Methods Enzymol. 1977, 47: 165–170. PMID 927173. doi:10.1016/0076-6879(77)47020-4. 
  2. ^ Gilles, A.-M., Imhoff, J.-M. and Keil, B. α-Clostripain. Chemical characterization, activity, and thiol content of the highly active form of clostripain. J. Biol. Chem. 1979, 254: 1462–1468. PMID 762145. 
  3. ^ Gilles, A.-M., Lecroisey, A. and Keil, B. Primary structure of α-clostripain light chain. Eur. J. Biochem. 1984, 145: 469–476. PMID 6391922. doi:10.1111/j.1432-1033.1984.tb08579.x. 

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