毡毛美洲茶素

化合物

毡毛美洲茶素(英語:Velutin)是从Xylosma velutina[1]巴西莓果中分离出来的化合物。[2]它被归类为黄酮

毡毛美洲茶素
IUPAC名
4′,5-Dihydroxy-3′,7-dimethoxyflavone
系统名
5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-4H-1-benzopyran-4-one
别名 Flavoyadorigenin B
识别
CAS号 25739-41-7  checkY
PubChem 5464381
ChemSpider 4576639
SMILES
 
  • COC1=CC(=C2C(=C1)OC(=CC2=O)C3=CC(=C(C=C3)O)OC)O
InChI
 
  • 1/C17H14O6/c1-21-10-6-12(19)17-13(20)8-14(23-16(17)7-10)9-3-4-11(18)15(5-9)22-2/h3-8,18-19H,1-2H3
InChIKey ROCUOVBWAWAQFD-UHFFFAOYAA
ChEBI 177047
性质
化学式 C17H14O6
摩尔质量 314.29 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

毡毛美洲茶素具有多种生物活性,例如皮肤美白(抗黑色素生成)作用,以及潜在的抗炎、抗过敏、抗氧化和抗菌活性。[3]

参考资料

  1. ^ Chang, P. T. Otto; Cordell, Geoffrey A.; Fong, Harry H. S.; Farnsworth, Norman R. Velutinic acid, a new friedelane derivative from Xylosma velutina (Flacourtiaceae). Phytochemistry. 1 January 1977, 16 (9): 1443–1445. Bibcode:1977PChem..16.1443C. doi:10.1016/S0031-9422(00)88804-4. 
  2. ^ Xie, C; Kang, J; Li, Z; Schauss, A. G.; Badger, T. M.; Nagarajan, S; Wu, T; Wu, X. The açaí flavonoid velutin is a potent anti-inflammatory agent: Blockade of LPS-mediated TNF-α and IL-6 production through inhibiting NF-κB activation and MAPK pathway. The Journal of Nutritional Biochemistry. 2012, 23 (9): 1184–91. PMID 22137267. doi:10.1016/j.jnutbio.2011.06.013. 
  3. ^ Jung, Se-Hui; Heo, Hee-Young; Choe, Jung-Won; Kim, Jaehyun; Lee, Kooyeon. Anti-Melanogenic Properties of Velutin and Its Analogs. Molecules (Basel, Switzerland). 2021-05-19, 26 (10): 3033. ISSN 1420-3049. PMC 8160911 . PMID 34069624. doi:10.3390/molecules26103033 .