氟硅唑

化合物

氟硅唑DPX-H6573)是一種由杜邦发明的有机硅杀真菌剂,用來控制各種水果和蔬菜農作物的真菌感染。[1][2][3]它對动物有中度毒性,大量攝入後可能會導致先天性障碍[4][5]

氟硅唑
IUPAC名
1[Bis(4-fluorophenyl)(methyl)silyl]methyl1H-1,2,4-triazole
别名 DPX-H6573;
识别
CAS号 85509-19-9  checkY
PubChem 73675
ChemSpider 66326
SMILES
 
  • c2ncnn2C[Si](C)(c(cc1)ccc1F)c3ccc(F)cc3
InChI
 
  • 1/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3
InChIKey FQKUGOMFVDPBIZ-UHFFFAOYAI
ChEBI 81922
性质
化学式 C16H15F2N3Si
摩尔质量 315.392 g/mol g·mol⁻¹
溶解性 41.9 mg/L (20°C)
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

外部鏈接

  • 氟硅唑 in the Pesticide Properties DataBase (PPDB)

參考文獻

  1. ^ Moberg, W. K.; Basarab, G. S.; Cuomo, J.; Liang, P. H. Biologically Active Organosilicon Compounds. Synthesis and Chemistry of Agrochemicals. ACS Symposium Series 355. 1987: 288–301. ISBN 9780841214347. doi:10.1021/bk-1987-0355.ch026. 
  2. ^ Bostanian NJ, Larocque N, Chouinard G, Coderre D. Baseline toxicity of several pesticides to Hyaliodes vitripennis (Say) (Hemiptera: Miridae). Pest Management Science. November 2001, 57 (11): 1007–10. PMID 11721516. doi:10.1002/ps.374. 
  3. ^ Eckert MR, Rossall S, Selley A, Fitt BD. Effects of fungicides on in vitro spore germination and mycelial growth of the phytopathogens Leptosphaeria maculans and L. biglobosa (phoma stem canker of oilseed rape). Pest Management Science. April 2010, 66 (4): 396–405. PMID 20013877. doi:10.1002/ps.1890 . 
  4. ^ Farag AT, Ibrahim HH. Developmental toxic effects of antifungal flusilazole administered by gavage to mice. Birth Defects Research Part B: Developmental and Reproductive Toxicology. February 2007, 80 (1): 12–7. PMID 17187383. doi:10.1002/bdrb.20098. 
  5. ^ Hermsen SA, van den Brandhof EJ, van der Ven LT, Piersma AH. Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies. Toxicology in Vitro. January 2011, 25 (3): 745–753. PMID 21238576. doi:10.1016/j.tiv.2011.01.005 .