4-碘苯甲腈
化合物
4-碘苯甲腈是一种有机化合物,化学式为C7H4IN。它可由4-碘苯甲醛在DMPU盐酸盐的存在下和盐酸羟胺反应制得,[2]或由4-氰基苯胺、碘和亚硝酸叔丁酯反应得到。[3]它和苯硼酸在钯催化剂和碱(如碳酸钾)存在下反应,可以得到4-氰基联苯。[4]
4-碘苯甲腈 | |
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别名 | 对碘苯甲腈 4-氰基碘苯 对氰基碘苯 |
识别 | |
CAS号 | 3058-39-7 ![]() |
性质 | |
化学式 | C7H4IN |
摩尔质量 | 229.02 g·mol−1 |
熔点 | 123—125 °C(396—398 K)[1] |
相关物质 | |
其他阴离子 | 4-氟苯甲腈 4-氯苯甲腈 4-溴苯甲腈 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
参考文献
- ^ Amin Zarei, Abdol Hajipour, Leila Khazdooz. A One-Pot Method for the Iodination of Aryl Amines via Stable Aryl Diazonium Silica Sulfates Under Solvent-Free Conditions. Synthesis. 2009-03-02, 2009 (06): 941–944 [2021-12-22]. ISSN 0039-7881. doi:10.1055/s-0028-1087981. (原始内容存档于2018-06-03) (英语).
- ^ Mudshinge, Sagar R.; Potnis, Chinmay S.; Xu, Bo; Hammond, Gerald B. HCl·DMPU-assisted one-pot and metal-free conversion of aldehydes to nitriles. Green Chemistry (Royal Society of Chemistry (RSC)). 2020, 22 (13): 4161–4164. ISSN 1463-9262. doi:10.1039/d0gc00757a.
- ^ Malet-Sanz, Laia; Madrzak, Julia; Holvey, Rhian S.; Underwood, Toby. A safe and reliable procedure for the iododeamination of aromatic and heteroaromatic amines in a continuous flow reactor. Tetrahedron Letters (Elsevier BV). 2009, 50 (52): 7263–7267. ISSN 0040-4039. doi:10.1016/j.tetlet.2009.10.007.
- ^ Eskedar Tessema, Vijayanath Elakkat, Chiao-Fan Chiu, Zong-Lin Tsai, Ka Long Chan, Chia-Rui Shen, Han-Chang Su, Norman Lu. Recoverable Palladium-Catalyzed Carbon-Carbon Bond Forming Reactions under Thermomorphic Mode: Stille and Suzuki-Miyaura Reactions. Molecules. 2021-03-05, 26 (5): 1414 [2021-12-22]. ISSN 1420-3049. doi:10.3390/molecules26051414. (原始内容存档于2021-12-22) (英语).