4-肼基吡啶
化合物
4-肼基吡啶是一种有机化合物，化学式为C5H7N3，它可由4-氯吡啶和水合肼在1-丙醇中回流得到。[1]它和1,4-二(溴甲基)苯反应，得到吡啶氮烷基化的双季铵盐。[2]它和乙酰丙酮反应，可以得到4-(3,5-二甲基-1H-吡唑基)吡啶。[3]
| 4-肼基吡啶 | |
|---|---|
| |
| 别名 | 4-吡啶肼 |
| 识别 | |
| CAS号 | 27256-91-3 
|
| 性质 | |
| 化学式 | C5H7N3 |
| 摩尔质量 | 109.13 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
参考文献
- ^ Sülünay Parlar, Yalçın Erzurumlu, Recep Ilhan, Petek Ballar Kırmızıbayrak, Vildan Alptüzün, Ercin Erciyas. Synthesis and evaluation of pyridinium-hydrazone derivatives as potential antitumoral agents. Chemical Biology & Drug Design. 2018-07, 92 (1): 1198–1205 [2022-03-05]. doi:10.1111/cbdd.13177. （原始内容存档于2022-03-05） （英语）.
- ^ Arturo Blanco-Gómez, Iago Neira, José L. Barriada, Manuel Melle-Franco, Carlos Peinador, Marcos D. García. Thinking outside the “Blue Box”: from molecular to supramolecular pH-responsiveness. Chemical Science. 2019, 10 (46): 10680–10686 [2022-03-05]. ISSN 2041-6520. PMC 7069232
. PMID 32206250. doi:10.1039/C9SC04489B （英语）.
- ^ Badescu, Valentina O.; Camp, Anne Marie; Clark, Barry Peter; Cohen, Michael Philip; Filla, Sandra Ann; Gallagher, Peter Thaddeus; Hellman, Sarah Lynne; Mazanetz, Michael Philip; Pineiro-Nunez, Marta Maria; Schaus, John Mehnert; Spinazze, Patrick Gianpietro; Whatton, Maria Ann. 2-[4-(Pyrazol-4-ylalkyl)piperazin-1-yl]-3-phenylpiperazines and pyridines and 3-[4-(pyrazol-4-ylalkyl)piperazin-1-yl]-2-phenylpyridines as 5-HT7 receptor antagonist and their preparation and use in the treatment of migraine, persistent pain and anxiety. 2008 WO 2008141020 A1.
