D75-4590
化合物
D75-4590是一种含氮有机化合物，分子式C21H27N5，属于吡多苯并咪唾衍生物，可作为抗真菌药，抑制真菌的β-葡聚糖生物合成[1][2]。
| D75-4590 | |
|---|---|
| |
| IUPAC名 1[2-(Diethylamino)ethyl]amino2-ethyl-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile | |
| 别名 | 4-[2-(Diethylamino)ethylamino]-3-ethyl-2-methyl-4a,9-diaza-3,4-dihydrofluorene-1-carbonitrile |
| 识别 | |
| CAS号 | 384376-42-5 
|
| PubChem | 948175 |
| ChemSpider | 824252 |
| SMILES |
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| 性质 | |
| 化学式 | C21H27N5 |
| 摩尔质量 | 349.473 g/mol g·mol⁻¹ |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
参考文献
- ^ Kitamura, Akihiro; Someya, Kazuhiko; Hata, Masato; Nakajima, Ryohei; Takemura, Makoto. Discovery of a Small-Molecule Inhibitor of β-1,6-Glucan Synthesis. Antimicrobial Agents and Chemotherapy. 2008, 53 (2): 670–7. PMC 2630612
. PMID 19015325. doi:10.1128/AAC.00844-08.
- ^ Kitamura, Akihiro; Someya, Kazuhiko; Okumura, Ryo; Hata, Masato; Takeshita, Hiroshi; Nakajima, Ryohei. In Vitro Antifungal Activities of D11-2040, a β-1,6-Glucan Inhibitor, with or without Currently Available Antifungal Drugs. Biological & Pharmaceutical Bulletin. 2010, 33 (2): 192–7. PMID 20118539. doi:10.1248/bpb.33.192 .
