PMP2

Peripheral myelin protein 2
外周髓鞘蛋白2
Peripheral myelin protein 2; 外周髓鞘蛋白2
	PDB rendering based on 1pmp.
有效结构
PDB	直系同源检索：PDBe, RCSB
PDB查询代码列表
	2WUT, 3NR3, 4A1H, 4A1Y, 4A8Z
标识
代号	PMP2; FABP8; M-FABP; MP2; P2
扩展标识	遗传学：170715 鼠基因：102667 同源基因：20589 GeneCards: PMP2 Gene
基因本体论描述
分子功能	· transporter activity; · fatty acid binding; · cholesterol binding;
细胞成分	· cytoplasm;
生物过程	· membrane organization;
	Sources: Amigo / QuickGO
RNA表达模式
	更多表达数据
直系同源体
物种	人类
Entrez	5375
Ensembl	ENSG00000147588
UniProt	P02689
mRNA序列	NM_002677
蛋白序列	NP_002668
基因位置	Chr 8:; 82.35 – 82.36 Mb
PubMed查询	[1]
	查; 论; 编;

髓鞘蛋白P2（英語：Myelin P2 protein）是一个由人类基因 PMP2 编码的蛋白质^[1]^[2]^[3]。

参考文献

^ Hayasaka K, Nanao K, Tahara M, Sato W, Takada G, Miura M, Uyemura K. Isolation and sequence determination of cDNA encoding P2 protein of human peripheral myelin. Biochem Biophys Res Commun. Jan 1992, 181 (1): 204–7. PMID 1720307. doi:10.1016/S0006-291X(05)81402-0.
^ Hayasaka K, Himoro M, Takada G, Takahashi E, Minoshima S, Shimizu N. Structure and localization of the gene encoding human peripheral myelin protein 2 (PMP2). Genomics. Feb 1994, 18 (2): 244–8. PMID 8288226. doi:10.1006/geno.1993.1462.
^ Entrez Gene: PMP2 peripheral myelin protein 2.

延伸阅读

Narayanan V, Barbosa E, Reed R, Tennekoon G. Characterization of a cloned cDNA encoding rabbit myelin P2 protein. J. Biol. Chem. 1988, 263 (17): 8332–7. PMID 2453513.
Jones TA, Bergfors T, Sedzik J, Unge T. The three-dimensional structure of P2 myelin protein. EMBO J. 1988, 7 (6): 1597–604. PMC 457142  . PMID 2458918.
Ishaque A, Hofmann T, Eylar EH. The complete amino acid sequence of the rabbit P2 protein. J. Biol. Chem. 1982, 257 (2): 592–5. PMID 6172423.
Suzuki M, Kitamura K, Sakamoto Y, Uyemura K. The complete amino acid sequence of human P2 protein. J. Neurochem. 1983, 39 (6): 1759–62. PMID 6183401. doi:10.1111/j.1471-4159.1982.tb08017.x.
Trapp BD, Dubois-Dalcq M, Quarles RH. Ultrastructural localization of P2 protein in actively myelinating rat Schwann cells. J. Neurochem. 1984, 43 (4): 944–8. PMID 6206203. doi:10.1111/j.1471-4159.1984.tb12828.x.
Narayanan V, Ripepi B, Jabs EW; et al. Partial structure and mapping of the human myelin P2 protein gene. J. Neurochem. 1994, 63 (6): 2010–3. PMID 7525873. doi:10.1046/j.1471-4159.1994.63062010.x.
Besançon R, Latour P, Lara K; et al. Exonic SNPs at positions 220 (A/G) and 445 (C/T) of the peripheral myelin protein 2 (PMP2). Hum. Mutat. 2001, 17 (3): 237. PMID 11241848. doi:10.1002/humu.11.
Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241  . PMID 12477932. doi:10.1073/pnas.242603899.
Fortna A, Kim Y, MacLaren E; et al. Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution. PLoS Biol. 2006, 2 (7): E207. PMC 449870  . PMID 15252450. doi:10.1371/journal.pbio.0020207.
Gerhard DS, Wagner L, Feingold EA; et al. The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC). Genome Res. 2004, 14 (10B): 2121–7. PMC 528928  . PMID 15489334. doi:10.1101/gr.2596504.

[pmid1720307-1] Hayasaka K, Nanao K, Tahara M, Sato W, Takada G, Miura M, Uyemura K. Isolation and sequence determination of cDNA encoding P2 protein of human peripheral myelin. Biochem Biophys Res Commun. Jan 1992, 181 (1): 204–7. PMID 1720307. doi:10.1016/S0006-291X(05)81402-0.

[pmid8288226-2] Hayasaka K, Himoro M, Takada G, Takahashi E, Minoshima S, Shimizu N. Structure and localization of the gene encoding human peripheral myelin protein 2 (PMP2). Genomics. Feb 1994, 18 (2): 244–8. PMID 8288226. doi:10.1006/geno.1993.1462.

[entrez-3] Entrez Gene: PMP2 peripheral myelin protein 2.

[1]

[2]

[3]