苯异丙肼
化合物
苯异丙肼(英語:Pheniprazine或amphethydrazine、amphetamine hydrazide,商品名:Catron、Cavodil,开发代号:JB-516)是一种有机化合物,化学式为C9H14N2,属于聯氨类单胺氧化酶抑制剂(MAOI),1960年代开始作为抗抑郁药使用[2][3][4]。
臨床資料 | |
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给药途径 | Oral |
ATC碼 |
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法律規範狀態 | |
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识别信息 | |
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CAS号 | 55-52-7 |
PubChem CID | |
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ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.000.215 |
化学信息 | |
化学式 | C9H14N2 |
摩尔质量 | 150.23 g·mol−1 |
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参考文献
- ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-03-31 (2023-04-04) [2023-08-16]. (原始内容存档于2023-08-03) (巴西葡萄牙语).
- ^ Lear TE, Browne MW, Greeves JA. A controlled trial of cavodil (pheniprazine) in depression. The Journal of Mental Science. November 1962, 108 (457): 856–58. PMID 13928843. doi:10.1192/bjp.108.457.856.
- ^ Fagervall I, Ross SB. Inhibition of monoamine oxidase in monoaminergic neurones in the rat brain by irreversible inhibitors. Biochemical Pharmacology. April 1986, 35 (8): 1381–7. PMID 2870717. doi:10.1016/0006-2952(86)90285-6.
- ^ Eberson LE, Persson K. Studies on Monoamine Oxidase Inhibitors. I. The Autoxidation of β-Phenylisopropylhydrazine as a Model Reaction for Irreversible Monoamine Oxidase Inhibition. Journal of Medicinal and Pharmaceutical Chemistry. July 1962, 91 (4): 738–52. PMID 14056405. doi:10.1021/jm01239a006.