苯異丙肼

化合物

苯異丙肼(英語:Pheniprazineamphethydrazineamphetamine hydrazide,商品名:CatronCavodil,開發代號:JB-516)是一種有機化合物,化學式為C9H14N2,屬於聯氨單胺氧化酶抑制劑(MAOI),1960年代開始作為抗抑鬱藥使用[2][3][4]

苯異丙肼
臨床資料
給藥途徑Oral
ATC碼
  • 未分配
法律規範狀態
法律規範
  • Uncontrolled
識別資訊
  • (1-Methyl-2-phenyl-ethyl)hydrazine
CAS號55-52-7  checkY
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.000.215 編輯維基數據鏈接
化學資訊
化學式C9H14N2
摩爾質量150.23 g·mol−1
  • InChI=1S/C9H14N2/c1-8(11-10)7-9-5-3-2-4-6-9/h2-6,8,11H,7,10H2,1H3 checkY
  • Key:VXTWEDPZMSVFEF-UHFFFAOYSA-N checkY

參考文獻

  1. ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-03-31 (2023-04-04) [2023-08-16]. (原始內容存檔於2023-08-03) (巴西葡萄牙語). 
  2. ^ Lear TE, Browne MW, Greeves JA. A controlled trial of cavodil (pheniprazine) in depression. The Journal of Mental Science. November 1962, 108 (457): 856–58. PMID 13928843. doi:10.1192/bjp.108.457.856. 
  3. ^ Fagervall I, Ross SB. Inhibition of monoamine oxidase in monoaminergic neurones in the rat brain by irreversible inhibitors. Biochemical Pharmacology. April 1986, 35 (8): 1381–7. PMID 2870717. doi:10.1016/0006-2952(86)90285-6. 
  4. ^ Eberson LE, Persson K. Studies on Monoamine Oxidase Inhibitors. I. The Autoxidation of β-Phenylisopropylhydrazine as a Model Reaction for Irreversible Monoamine Oxidase Inhibition. Journal of Medicinal and Pharmaceutical Chemistry. July 1962, 91 (4): 738–52. PMID 14056405. doi:10.1021/jm01239a006. 

外部連結