蛙粪霉病

蛙粪霉病(Basidiobolomycosis)是蛙生蛙糞霉造成的感染[4][5],症狀多為皮膚上結實並稍帶紫色的結節[2][5],一般為無痛,但也可能有癢或痛感[2][5];少數則為感染腸胃道,造成腹痛發燒等症狀[2]。蛙生蛙糞霉生長在土壤、腐爛的蔬菜與昆蟲等動物體內[1],透過傷口(如蟲咬英语Arthropod bites and stings)或飲食感染人類[2][4]。此病可透過醫學影像活體組織檢查顯微鏡檢查病原培養與組織病理學分析等方式診斷[1],以手術切除病灶或两性霉素B抗真菌药治療[2][3]

蛙糞霉病
造成感染的蛙生蛙粪霉
症状皮膚上的結節[1]、腹痛[2]
起病年龄漸進式/緩慢[1]
病因蛙生蛙粪霉[1]
診斷方法醫學影像活體組織檢查顯微鏡學、病原培養、組織病理學[1]
鑑別診斷炎症性肠病[1]
治療抗真菌药、手術切除[3]
藥物两性霉素B[3]
患病率罕見[2]
分类和外部资源
醫學專科傳染病學[4]
ICD-111F21
ICD-10B46.8
DiseasesDB33790
[编辑此条目的维基数据]

蛙生蛙糞霉可見於世界各地,但蛙粪霉病多見於熱帶亞熱帶地區,包括非洲、南美洲、亞洲與美國西南部[2],為一罕見的真菌感染疾病[2],男性與兒童的感染率高於女性[2]。首例病例發生於1956年,為一名皮膚被感染的印尼患者[3]。1964年出現首例腸胃道感染患者[3]。除人類外,也有被感染的紀錄[6]

參考文獻

  1. ^ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Queiroz-Telles, Flavio; Fahal, Ahmed Hassan; Falci, Diego R.; Caceres, Diego H.; Chiller, Tom; Pasqualotto, Alessandro C. Neglected endemic mycoses. The Lancet. Infectious Diseases. November 2017, 17 (11): e367–e377. ISSN 1474-4457. PMID 28774696. doi:10.1016/S1473-3099(17)30306-7. 
  2. ^ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 Bering, Jamie; Mafi, Neema; Vikram, Holenarasipur R. Basidiobolomycosis: an unusual, mysterious, and emerging endemic fungal infection . Paediatrics and International Child Health. May 2018, 38 (2): 81–84. ISSN 2046-9055. PMID 29846151. S2CID 44181507. doi:10.1080/20469047.2018.1458772. 
  3. ^ 3.0 3.1 3.2 3.3 3.4 Geramizadeh, Bita; Heidari, Mina; Shekarkhar, Golsa. Gastrointestinal Basidiobolomycosis, a Rare and Under-diagnosed Fungal Infection in Immunocompetent Hosts: A Review Article. Iranian Journal of Medical Sciences. March 2015, 40 (2): 90–97. ISSN 0253-0716. PMC 4359942 . PMID 25821287. 
  4. ^ 4.0 4.1 4.2 Al Jarie, A.; Al Azraki, T.; Al Mohsen, I.; Al Jumaah, S.; Almutawa, A.; Mohd Fahim, Y.; Al Shehri, M.; Abu Dayah, A.; Ibrahim, A.; Maw Shabana, M.; Rezk Abd-Elwahed Hussein, M. Basidiobolomycosis: Case series. Journal de Mycologie Médicale. March 2011, 21 (1): 37–45. ISSN 1156-5233. PMID 24451502. doi:10.1016/j.mycmed.2010.11.002. 
  5. ^ 5.0 5.1 5.2 ICD-11 - ICD-11 for Mortality and Morbidity Statistics. icd.who.int. [22 May 2021]. 
  6. ^ OKADA, Kazuki; AMANO, Shinjiro; KAWAMURA, Yoshio; KAGAWA, Yumiko. Gastrointestinal basidiobolomycosis in a dog. The Journal of Veterinary Medical Science. October 2015, 77 (10): 1311–1313. ISSN 0916-7250. PMC 4638302 . PMID 25960121. doi:10.1292/jvms.15-0177.