利米特罗

化合物

利米特罗INN:rimiterol)是第三代[1]短效β2肾上腺素受体激动剂[2][3]该药物可通过静脉注射气雾给药[4]利米特罗可用于治疗与支气管哮喘相关的支气管痉挛[5][6][7]

利米特罗
临床资料
怀孕分级
  • : A
ATC码
法律规范状态
法律规范
识别信息
  • 4-{(S)-hydroxy[(2R)-piperidin-2-yl]methyl}benzene-1,2-diol
CAS号32953-89-2  ☒N
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.046.627 编辑维基数据链接
化学信息
化学式C12H17NO3
摩尔质量223.27 g·mol−1
3D模型(JSmol英语JSmol
  • O[C@@H](c1ccc(O)c(O)c1)[C@@H]2NCCCC2
  • InChI=1S/C12H17NO3/c14-10-5-4-8(7-11(10)15)12(16)9-3-1-2-6-13-9/h4-5,7,9,12-16H,1-3,6H2/t9-,12+/m1/s1 checkY
  • Key:IYMMESGOJVNCKV-SKDRFNHKSA-N checkY

参见

参考资料

  1. ^ Palma-Carlos AG, Palma-Carlos GS. Beta-2-agonists of third generation. Allergie et Immunologie. April 1986, 18 (4): 31–2, 35. PMID 2899434. 
  2. ^ Lai CK, Twentyman OP, Holgate ST. The effect of an increase in inhaled allergen dose after rimiterol hydrobromide on the occurrence and magnitude of the late asthmatic response and the associated change in nonspecific bronchial responsiveness. The American Review of Respiratory Disease. October 1989, 140 (4): 917–23. PMID 2572192. doi:10.1164/ajrccm/140.4.917. 
  3. ^ Ydreborg SO, Svedmyr N, Thiringer G. Comparison of rimiterol and terbutaline, given by aerosol, in a long-term study. Scandinavian Journal of Respiratory Diseases. April 1977, 58 (2): 117–24. PMID 16339. 
  4. ^ Tarala, R. A.; Martyn, V.; Paterson, J. W. Effect of intravenous injection of rimiterol in asthma. British Journal of Clinical Pharmacology. 1981-09, 12 (3) [2024-03-24]. ISSN 0306-5251. PMC 1401816 . PMID 6117302. doi:10.1111/j.1365-2125.1981.tb01222.x. (原始内容存档于2024-03-24). 
  5. ^ Linehan, W. D. A new bronchodilator, rimiterol hydrobromide (R 798): an open study of the bronchodilator, cardiovascular and arterial oxygen changes in asthmatic patients. Irish Journal of Medical Science. 1975-04, 144 (4) [2024-03-24]. ISSN 0021-1265. PMID 238916. (原始内容存档于2024-03-24). 
  6. ^ Muittari, A. A comparison of rimiterol and salbutamol by inhalation at high and low dose in asthmatic patients. Respiration; International Review of Thoracic Diseases. 1978, 35 (3) [2024-03-24]. ISSN 0025-7931. PMID 25466. doi:10.1159/000193873. (原始内容存档于2024-03-24). 
  7. ^ Pinder, R. M.; Brogden, R. N.; Speight, T. M.; Avery, G. S. Rimiterol: a review of its pharmacological properties and therapeutic efficacy in asthma. Drugs. 1977-08, 14 (2) [2024-03-24]. ISSN 0012-6667. PMID 19226. doi:10.2165/00003495-197714020-00001. (原始内容存档于2024-03-24).