异硫氰酸三甲基硅酯
化合物
异硫氰酸三甲基硅酯是一种有机硅化合物，化学式为(CH3)3SiNCS。它可用于1,3,4-𫫇二唑的合成。[5]
| Trimethylsilyl isothiocyanate | |
|---|---|
| |
[[File: |200px|alt=|]]
| |
| IUPAC名 isothiocyanato(trimethyl)silane[1] | |
| 别名 | TMSNCS、三甲基硅基异硫氰酸酯 |
| 识别 | |
| CAS号 | 2290-65-5 
|
| PubChem | 75297 |
| ChemSpider | 67839 |
| SMILES |
|
| EINECS | 218-929-7 |
| 性质 | |
| 化学式 | C4H9NSSi |
| 摩尔质量 | 131.27 g·mol−1 |
| 密度 | 0.931 g·mL−1 [2] |
| 熔点 | −32.8 °C（240 K） |
| 沸点 | 143 °C（416 K） |
| 溶解性（水） | Reacts with water[3] |
| 蒸气压 | 100 mmHg |
| 危险性 | |
GHS危险性符号    [4]
| |
| GHS提示词 | DANGER[4] |
| H-术语 | H226, H301, H311, H315, H319, H331, H334, H335 |
| NFPA 704 |
 2
3
0
|
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
合成
参考文献
- ^ Trimethylsilyl isothiocyanate (Compound). Pubchem. [April 9, 2020]. （原始内容存档于2023-03-21）.
- ^ (Trimethylsilyl)isothiocyanate. sigmaaldrich. [April 9, 2020].
- ^ Trimethylsilyl isothiocyanate, 94%. Alfa Aesar. Thermo Fisher Scientific. [April 9, 2020].
- ^ 4.0 4.1 Trimethylsilyl isothiocyanate. Summary of Classification and Labeling. European Chemicals Agency (ECHA). [April 9, 2020].
- ^ Guda, Dinneswara Reddy; Cho, Hyeon Mo; Lee, Myong Euy. Mild and convenient one-pot synthesis of 2-amino-1,3,4-oxadiazoles promoted by trimethylsilyl isothiocyanate (TMSNCS). RSC Advances. 2013, 3 (21): 7684 [10 April 2020]. Bibcode:2013RSCAd...3.7684G. doi:10.1039/C3RA41044G. （原始内容存档于2023-03-21）.
- ^ N. V. Zyk, A. Yu. Gavrilova, O. A. Mukhina, A. A. Borisenko, O. B. Bondarenko, N. S. Zefirov. Reaction of unsaturated compounds with ethyl benzenesulfenate and trimethylsilyl isothiocyanate. Russian Chemical Bulletin. 2010-09, 59 (9): 1771–1780 [2023-03-21]. ISSN 1066-5285. doi:10.1007/s11172-010-0311-0 （英语）.