扁平苔藓
扁平苔藓(Lichen planus)是一种表皮慢性病,属于丘疹鳞屑性疾患的一种,常见于皮肤、口腔、舌头。症状包含但不限于:丘疹[1],溃烂,瘙痒,红疹,白色斑片。可以在显微镜下观察切片而确诊。
扁平苔藓 Lichen planus | |
---|---|
扁平苔藓患者的皮肤 | |
类型 | lichen disease[*]、疾病 |
分类和外部资源 | |
医学专科 | 皮肤病学 |
ICD-11 | EA91 |
ICD-10 | L43 |
ICD-9-CM | 697.0 |
DiseasesDB | 7452 |
MedlinePlus | 000867 |
eMedicine | derm/233 derm/663 |
MeSH | D008010 |
Orphanet | 254367 |
本病与苔藓完全无关,会令皮肤出现一种好像长在树干上的苔藓样的干燥波纹,因而得名。现时已知道病因可能与氧化压力(oxidative stress)相关[2][3],也与某些药物及疾病有关联,但在背后的病理机制及具体的发病原因尚不明确。
治疗
扁平苔藓现时未有特效的办法治疗。为舒缓病况,可使用消炎的口服药物或外敷药物,如糖皮质激素类药物地奈德。另外现时有其他研究使用以下方式治疗:
参考资料
- ^ 道兰氏医学词典中的lichen planus
- ^ Ioana Scrobotă, Teodora Mocan, C. Cătoi, P. Bolfă, Adriana Mureşan, G. Băciuţ. Histopathological aspects and local implications of oxidative stress in patients with oral lichen planus. Romanian Journal of Morphology and Embryology = Revue Roumaine De Morphologie Et Embryologie. 2011, 52 (4): 1305–1309 [2019-02-13]. ISSN 1220-0522. PMID 22203938. (原始内容存档于2019-08-13).
- ^ D. G. Aly, R. S. Shahin. Oxidative stress in lichen planus. Acta Dermatovenerologica Alpina, Pannonica, Et Adriatica. 2010, 19 (1): 3–11 [2019-02-13]. ISSN 1581-2979. PMID 20372767. (原始内容存档于2019-08-19).
- ^ Pavlotsky F, Nathansohn N, Kriger G, Shpiro D, Trau H. Ultraviolet-B treatment for cutaneous lichen planus: our experience with 50 patients. Photodermatol Photoimmunol Photomed. April 2008, 24 (2): 83–6. PMID 18353088. doi:10.1111/j.1600-0781.2008.00344.x.
- ^ Choonhakarn C, Busaracome P, Sripanidkulchai B, Sarakarn P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br. J. Dermatol. March 2008, 158 (3): 573–7. PMID 18093246. doi:10.1111/j.1365-2133.2007.08370.x.[永久失效链接]
- ^ Agha-Hosseini F, Borhan-Mojabi K, Monsef-Esfahani HR, Mirzaii-Dizgah I, Etemad-Moghadam S, Karagah A. Efficacy of purslane in the treatment of oral lichen planus. Phytother Res. Feb 2010, 24 (2): 240–4. PMID 19585472. doi:10.1002/ptr.2919.