醋酸炔诺酮

化合物

醋酸炔诺酮(或称为炔诺酮乙酸酯,英语:Norethisterone acetate 或 norethindrone acetate,缩写NETA,商品名有Primolut-Nor等)是一种有机化合物,分子式为C22H28O3,属于孕激素类药物[1],能用作复合口服避孕药,也作为妇科病激素替代疗法药物[2][3][4]

醋酸炔诺酮
临床资料
商品名英语Drug nomenclaturePrimolut-Nor, Aygestin, Gestakadin, Milligynon, Monogest, Norlutate, Primolut N, SH-420, Sovel, Styptin, others
其他名称NETA; NETAc; Norethindrone acetate; SH-420; 17α-Ethynyl-19-nortestosterone 17β-acetate; 17α-Ethynylestra-4-en-17β-ol-3-one 17β-acetate
AHFS/Drugs.com国际药品名称
MedlinePlusa604034
给药途径口服给药
药物类别英语Drug class孕激素
ATC码
法律规范状态
法律规范
  • 处方药(-only)
识别信息
  • (8R,9S,10R,13S,14S,17S)-17-ethynyl-13-methyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate
CAS号51-98-9  checkY
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.000.121 编辑维基数据链接
化学信息
化学式C22H28O3
摩尔质量340.46 g·mol−1
3D模型(JSmol英语JSmol
  • C[C@@]12[C@](OC(C)=O)(C#C)CC[C@]1([C@]3([C@](CC2)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])[H]
  • InChI=1S/C22H28O3/c1-4-22(25-14(2)23)12-10-20-19-7-5-15-13-16(24)6-8-17(15)18(19)9-11-21(20,22)3/h1,13,17-20H,5-12H2,2-3H3/t17-,18+,19+,20-,21-,22-/m0/s1 ☒N
  • Key:IMONTRJLAWHYGT-ZCPXKWAGSA-N ☒N

参考文献

  1. ^ Kuhl H. Pharmacology of estrogens and progestogens: influence of different routes of administration (PDF). Climacteric. August 2005, 8 (Suppl 1): 3–63 [2018-09-06]. PMID 16112947. S2CID 24616324. doi:10.1080/13697130500148875. (原始内容存档 (PDF)于2016-08-22). 
  2. ^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 886– [28 July 2017]. ISBN 978-1-4757-2085-3. (原始内容存档于10 January 2023). 
  3. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000: 750 [30 May 2012]. ISBN 978-3-88763-075-1. 
  4. ^ Norethindrone Monograph for Professionals. [2018-01-23]. (原始内容存档于2017-07-29).