ORG-2058

化合物

ORG-2058(化学名16α-乙基-21-羟基-19-去甲孕酮,英语:16α-ethyl-21-hydroxy-19-norprogesterone)是一种人工合成19-去甲孕酮衍生孕激素,分子式C22H32O3,从未上市销售[1][2]

ORG-2058
临床资料
其他名称16α-Ethyl-21-hydroxy-19-norprogesterone; 16α-Ethyl-21-hydroxy-19-norpregn-4-ene-3,20-dione
识别信息
  • (8R,9S,10R,13S,14S,16R,17S)-16-ethyl-17-(2-hydroxyacetyl)-13-methyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
CAS号24320-06-7
PubChem CID
ChemSpider
ChEMBL
化学信息
化学式C22H32O3
摩尔质量344.50 g·mol−1
3D模型(JSmol英语JSmol
  • CC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@@]2([C@H]1C(=O)CO)C
  • InChI=1S/C22H32O3/c1-3-13-11-19-18-6-4-14-10-15(24)5-7-16(14)17(18)8-9-22(19,2)21(13)20(25)12-23/h10,13,16-19,21,23H,3-9,11-12H2,1-2H3/t13-,16+,17-,18-,19+,21-,22+/m1/s1
  • Key:IJLXLZGJDSJGIQ-BILPMHSYSA-N

参考文献

  1. ^ Martin Negwer; Hans-Georg Scharnow. Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. 2001: 2350 [2023-06-12]. ISBN 978-3-527-30247-5. (原始内容存档于2023-01-14). 
  2. ^ Fleischmann, Gerhard; Beato, Miguel. Characterization of the progesterone receptor of rabbit uterus with the synthetic progestin 16α-ethyl-21-hydroxy-19-norpregn-4-ene-3,20-dione. Biochimica et Biophysica Acta (BBA) - General Subjects. 1978, 540 (3): 500–517. ISSN 0304-4165. doi:10.1016/0304-4165(78)90180-0. 

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