3-(4-氟苯基)-2-哌嗪酮

3-(4-氟苯基)-2-哌嗪酮是一種有機化合物,化學式為C10H11FN2O。它可以α-溴-4-氟苯乙酸甲酯、甲醇鈉乙二胺為原料反應製得。[1]它和二碳酸二叔丁酯反應,可以得到3-(4-氟苯基)哌嗪-2-酮-1-甲酸叔丁酯。[2]

3-(4-氟苯基)-2-哌嗪酮
識別
CAS號 85606-96-8  checkY
SMILES
 
  • O=C1NCCNC1C2=CC=C(F)C=C2
性質
化學式 C10H11FN2O
摩爾質量 194.21 g·mol−1
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考文獻

  1. ^ Davis, Jeremy Martin; Langham, Barry John; Naik, Manisha; Brookings, Daniel Christopher; Cubbon, Rachel Jane; Franklin, Richard Jeremy. Preparation of pyridine and pyrimidine derivatives as p38α kinase inhibitors. 2003. WO2003045941.
  2. ^ Hoveyda, Hamid R.; Roy, Marie-Odile; Fraser, Graeme L.; Dutheuil, Guillaume. Preparation of triazolopyrazines as novel NK-3 receptor selective antagonists, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders. 2015. US20150315199.