S-烯丙基半胱氨酸

S-烯丙基半胱氨酸簡稱SAC,是化學式HO
2
CCH(NH
2
)CH
2
SCH
2
C=CH
2
有機硫化合物氨基酸半胱氨酸S-烯丙基衍生物。與相關化合物S-烯丙硫基半胱氨酸(SAMC,HO
2
CCH(NH
2
)CH
2
SSCH
2
C=CH
2
)及γ-穀氨酰基-S-烯丙基半胱氨酸(GSAC)一樣,S-烯丙基半胱氨酸存在於老中。[1]它因有潛力用作藥物[2]化學預防劑英語Chemopreventive agent[3]而受到關注。

S-烯丙基半胱氨酸
IUPAC名
(R)-2-Amino-3-prop-2-enylsulfanylpropanoic acid
識別
縮寫 SAC
CAS號 21593-77-1  checkY
PubChem 9793905
ChemSpider 7969672
SMILES
 
  • O=C(O)[C@@H](N)CSC\C=C
InChI
 
  • 1/C6H11NO2S/c1-2-3-10-4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-/m0/s1
InChIKey ZFAHNWWNDFHPOH-YFKPBYRVBL
性質
化學式 C6H11NO2S
摩爾質量 161.22 g·mol−1
密度 1.191 ± 0.06 g/cm3
熔點 219—220 °C(426—428 °F;492—493 K)
相關物質
相關化學品 蒜氨酸
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

參考資料

  1. ^ Fujii, Takuto; Matsutomo, Toshiaki; Kodera, Yukihiro. Changes of S-Allylmercaptocysteine and γ-Glutamyl-S-allylmercaptocysteine Contents and Their Putative Production Mechanisms in Garlic Extract during the Aging Process. Journal of Agricultural and Food Chemistry. 2018, 66 (40): 10506–10512. PMID 30226990. S2CID 52297055. doi:10.1021/acs.jafc.8b02541. 
  2. ^ Yeh YY, Liu L. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies. Journal of Nutrition. 2001, 131 (3s): 989S–93S. PMID 11238803. doi:10.1093/jn/131.3.989S . 
  3. ^ Arora, Annu; Tripathi, Chitra; Shukla, Yogeshwer. Garlic and its organosulfides as potential chemopreventive agents: a review. Current Cancer Therapy Reviews. 2005, 1 (2): 199–205. doi:10.2174/1573394054021772. 

外部連結