JWH-359

化合物

JWH-359,分子式C24H36O2,是一種人工合成的二苯並吡喃型JWH系列大麻素,由約翰·威廉·霍夫曼合成,其苯環上1號位羥基形成了甲醚,側鏈上帶有二甲基和一個手性甲基[1][2]

JWH-359
識別資訊
  • (6aR,10aR)- 1-Methoxy- 6,6,9-trimethyl- 3-[(2R)-1,1,2-trimethylbutyl]- 6a,7,10,10a-tetrahydrobenzo[c]chromene
PubChem CID
ChemSpider
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C24H36O2
摩爾質量356.55 g·mol−1
3D模型(JSmol英語JSmol
  • C[C@H](CC)C(C)(C)c1cc2OC(C)(C)[C@@H]3CC=C(C)C[C@H]3c2c(OC)c1
  • InChI=1S/C24H36O2/c1-9-16(3)23(4,5)17-13-20(25-8)22-18-12-15(2)10-11-19(18)24(6,7)26-21(22)14-17/h10,13-14,16,18-19H,9,11-12H2,1-8H3/t16-,18-,19-/m1/s1
  • Key:BDJRWUBZMGSKHL-BHIYHBOVSA-N

參考文獻

  1. ^ Huffman JW, Bushell SM, Joshi SN, Wiley JL, Martin BR. Enantioselective synthesis of 1-methoxy- and 1-deoxy-2'-methyl-delta8-tetrahydrocannabinols: new selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. January 2006, 14 (1): 247–62. PMID 16165365. doi:10.1016/j.bmc.2005.08.013. 
  2. ^ Marriott KS, Huffman JW. Recent advances in the development of selective ligands for the cannabinoid CB(2) receptor. Current Topics in Medicinal Chemistry. 2008, 8 (3): 187–204. PMID 18289088. doi:10.2174/156802608783498014. 

外部連結