25N-N1-Nap是一種含氮有機化合物,化學式C21H22N2O4,屬於苯乙胺衍生物中的25-NB類,帶有基團,能作為5-HT2A受體英語5-HT2A receptor的強效激動劑[1][2]

25N-N1-Nap
識別資訊
  • N-[(naphthalen-1-yl)methyl]-1-(2,5-dimethoxy-4-nitrophenyl)-2-aminoethane
CAS號2865185-31-3  checkY
化學資訊
化學式C21H22N2O4
摩爾質量366.42 g·mol−1
3D模型(JSmol英語JSmol
  • COc1cc(CCNCc2cccc3ccccc32)c(cc1[N+]([O-])=O)OC
  • InChI=1S/C21H22N2O4/c1-26-20-13-19(23(24)25)21(27-2)12-16(20)10-11-22-14-17-8-5-7-15-6-3-4-9-18(15)17/h3-9,12-13,22H,10-11,14H2,1-2H3
  • Key:ALVHBRTUOXXMDK-UHFFFAOYSA-N

參考文獻

  1. ^ WO 2022241006,Wallach J, McCorvy J, Halberstadt A,「Selective, Partial and Arrestin-Biased 5-HT2A Agonists with Utility in Various Disorders.」,發表於17 November 2022,指定於Saint Joseph's University, The Medical College Of Wisconsin, Inc., The Regents Of The University Of California 
  2. ^ Wallach J, Cao AB, Calkins MM, Heim AJ, Lanham JK, Bonniwell EM, et al. Identification of 5-HT2A Receptor Signaling Pathways Responsible for Psychedelic Potential. bioRxiv. July 2023. PMC 10418054 . PMID 37577474. doi:10.1101/2023.07.29.551106. 

外部連結