細胞色素P450 1A2(英語:Cytochrome P450 1A2 (縮寫為CYP1A2),是細胞色素P450混合功能氧化家族的一員,參與體內異生物質的代謝[1]CYP1A2酶由人類CYP1A2基因編碼。[2]

Cytochrome P450, family 1, subfamily A, polypeptide 2
PDB根據2hi4所繪製的渲染圖
有效結構
PDB 直系同源檢索:PDBe, RCSB
標識
代號 CYP1A2; CP12; P3-450; P450(PA)
擴展標識 遺傳學124060 鼠基因88589 同源基因68082 ChEMBL: 3356 GeneCards: CYP1A2 Gene
EC編號 1.14.14.1
RNA表達模式
更多表達數據
直系同源體
物種 人類 小鼠
Entrez 1544 13077
Ensembl ENSG00000140505 ENSMUSG00000032310
UniProt P05177 P00186
mRNA序列 NM_000761 NM_009993
蛋白序列 NP_000752 NP_034123
基因位置 Chr 15:
74.75 – 74.76 Mb
Chr 9:
57.68 – 57.68 Mb
PubMed查詢 [1] [2]

引用

  1. ^ Nelson DR, Zeldin DC, Hoffman SM, Maltais LJ, Wain HM, Nebert DW. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants. Pharmacogenetics. January 2004, 14 (1): 1–18. PMID 15128046. doi:10.1097/00008571-200401000-00001. 
  2. ^ Jaiswal AK, Nebert DW, McBride OW, Gonzalez FJ. Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15. J. Exp. Pathol. 1987, 3 (1): 1–17. PMID 3681487. 

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