多依雌酸

化合物

多依雌酸(英语:Doisynoestrol,商品名有Fenocyclin、Surestrine、Surestryl等,开发名RS-2874),分子式C19H22O3,是一种道益酸类非甾体雌激素,已不再上市销售[1],可看做双脱氢道益酸(BDDA)的甲基醚[2]

多依雌酸
临床资料
商品名英语Drug nomenclatureFenocyclin, Surestrine, Surestryl
其他名称Diosynestrol; Fenocycline; Fenocyclin; Phenocyclin; RS-2874; Dehydrofolliculinic acid; cis-Bisdehydrodoisynolic acid 7-methyl ether; BDDA ME; NSC-56846; NSC-122041
给药途径By mouth
药物类别英语Drug classNonsteroidal estrogen
识别信息
  • 1-Ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-phenanthrene-2-carboxylic acid
CAS号15372-34-6
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C19H22O3
摩尔质量298.38 g·mol−1
3D模型(JSmol英语JSmol
  • CCC1C2=C(CCC1(C)C(=O)O)C3=C(C=C2)C=C(C=C3)OC
  • InChI=1S/C19H22O3/c1-4-17-16-7-5-12-11-13(22-3)6-8-14(12)15(16)9-10-19(17,2)18(20)21/h5-8,11,17H,4,9-10H2,1-3H3,(H,20,21)
  • Key:HZZSXUIUESWVSS-UHFFFAOYSA-N

参考文献

  1. ^ Elks J. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 465–. ISBN 978-1-4757-2085-3. 
  2. ^ Herbai G. Separation of growth inhibiting potency from oestrogenicity in different weak oestrogenic drugs of various chemical structures. Acta Endocrinologica. October 1971, 68 (2): 249–63. PMID 5171465. doi:10.1530/acta.0.0680249. 

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