COLO 205

細胞系

COLO 205(亦称ATCC CCL-222)是人类结肠癌细胞系[1],最初于1957年分离自一名70岁的白人男性结肠癌患者腹水,该患者已接受5-氟尿嘧啶治疗数周[2]。有研究指出COLO 205的标记染色体英语Marker chromosomeCOLO 201相同,并且发现在COLO 205及COLO 201细胞中出现的等臂染色体英语Isochromosome5在COLO 206细胞中不存在[2]。目前应用于细胞毒性测定和免疫球蛋白表征的免疫学研究[2]

参考资料

  1. ^ Björk, P; Jönsson, U; Svedberg, H; Larsson, K; Lind, P; Dillner, J; Hedlund, G; Dohlsten, M; Kalland, T. Isolation, partial characterization, and molecular cloning of a human colon adenocarcinoma cell-surface glycoprotein recognized by the C215 mouse monoclonal antibody.. The Journal of biological chemistry. 1993-11-15, 268 (32): 24232–41 [2019-12-09]. PMID 7693697. 
  2. ^ 2.0 2.1 2.2 Semple, TU; Quinn, LA; Woods, LK; Moore, GE. Tumor and lymphoid cell lines from a patient with carcinoma of the colon for a cytotoxicity model.. Cancer research. 1978-05, 38 (5): 1345–55 [2019-12-09]. PMID 565251. 

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