端锚聚合酶
位於8號人類染色體的基因
端锚聚合酶(英语:tankyrase),由人TNKS基因编码的酶[1][2][3]。它抑制TERF1与端粒DNA的结合。[4]
参考
- ^ Smith S, Giriat I, Schmitt A, de Lange T. Tankyrase, a poly(ADP-ribose) polymerase at human telomeres. Science. Dec 1998, 282 (5393): 1484–7. PMID 9822378. doi:10.1126/science.282.5393.1484.
- ^ Zhu L, Smith S, de Lange T, Seldin MF. Chromosomal mapping of the tankyrase gene in human and mouse. Genomics. May 1999, 57 (2): 320–1. PMID 10198177. doi:10.1006/geno.1999.5771.
- ^ Entrez Gene: TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase.
- ^ Cook, B. D.; Dynek, J. N.; Chang, W.; Shostak, G.; Smith, S. Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres. Molecular and Cellular Biology. 1 January 2002, 22 (1): 332–342. PMC 134233 . PMID 11739745. doi:10.1128/MCB.22.1.332-342.2002.