模板:Infobox gene/sandbox

络丝蛋白
已知的结构
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	2ddu、2e26、2DDU、2E26、3A7Q
识别号
别名	RELN；, LIS2, PRO1598, RL, reelin, ETL7
外部ID	OMIM：600514 MGI：103022 HomoloGene：3699 GeneCards：RELN
相关疾病
	阿尔茨海默病、耳硬化症、多发性硬化症、精神分裂症、Norman–Roberts syndrome、familial temporal lobe epilepsy 7
基因位置（人类）
染色体	7号染色体
终止	103,989,658 bp
基因位置（小鼠）
染色体	小鼠5号染色体
终止	22,549,700 bp
RNA表达模式
	查阅更多表达数据
基因本体
分子功能	• 金属离子结合; • 肽酶活性; • 水解酶活性; • serine-type peptidase activity; • lipoprotein particle receptor binding; • very-low-density lipoprotein particle receptor binding;
细胞组分	• 细胞质; • 树突; • 细胞膜; • 细胞外区域; • 细胞外空间; • 膜; • 细胞外间质; • neuron projection;
生物学过程	• NMDA glutamate receptor clustering; • positive regulation of lateral motor column neuron migration; • dendrite development; • 蛋白酶解; • 大脑皮质的组织发生; • lateral motor column neuron migration; • positive regulation of phosphatidylinositol 3-kinase signaling; • positive regulation of TOR signaling; • 长期记忆; • multicellular organism development; • receptor localization to synapse; • postsynaptic density protein 95 clustering; • ventral spinal cord development; • protein localization to synapse; • forebrain development; • 长时程增强作用; • 基因调节; • layer formation in cerebral cortex; • 细胞迁移; • 学习; • 联想型学习; • 细胞粘附; • hippocampus development; • spinal cord patterning; • cerebral cortex tangential migration; • positive regulation of peptidyl-tyrosine phosphorylation; • glial cell differentiation; • peptidyl-tyrosine phosphorylation; • positive regulation of excitatory postsynaptic potential; • positive regulation of CREB transcription factor activity; • positive regulation of protein kinase activity; • modulation of chemical synaptic transmission; • positive regulation of AMPA receptor activity; • brain development; • central nervous system development; • response to pain; • positive regulation of synapse maturation; • positive regulation of long-term synaptic potentiation; • cell morphogenesis involved in differentiation; • neuron migration; • positive regulation of neuron projection development; • positive regulation of small GTPase mediated signal transduction; • positive regulation of synaptic transmission, glutamatergic; • regulation of behavior; • positive regulation of dendritic spine morphogenesis; • reelin-mediated signaling pathway; • regulation of NMDA receptor activity; • positive regulation of protein tyrosine kinase activity; • 轴突导向;
	Sources:Amigo / QuickGO
直系同源
	5649
	19699
	ENSG00000189056
	ENSMUSG00000042453
	P78509
	Q60841
	NM_173054; NM_005045
	NM_011261; NM_001310464
	NP_005036; NP_774959
	NP_001297393; NP_035391
	维基数据
查看/编辑人类	查看/编辑小鼠

^ 與络丝蛋白相關的疾病；在維基數據上查看/編輯參考.
^ ^2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000189056 - Ensembl, May 2017
^ ^3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000042453 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[1] 與络丝蛋白相關的疾病；在維基數據上查看/編輯參考.

[refGRCh38Ensembl-2] 2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000189056 - Ensembl, May 2017

[refGRCm38Ensembl-3] 3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000042453 - Ensembl, May 2017

[4] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[1]

[2]

[3]

[4]

[5]