甲苯米定
化合物
甲苯米定（英語：Xylamidine）是一種含氮有機化合物，分子式C19H24N2O2，屬於5-HT1A受體拮抗劑，無法通過血腦屏障[1][2]。它可以3-甲氧基苯酚為原料經多步反應合成得到。[3]
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| CAS號 | 6443-50-1  |
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| 化學式 | C19H24N2O2 |
| 摩爾質量 | 312.41 g·mol−1 |
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參考文獻
- ^ Fuller RW, Kurz KD, Mason NR, Cohen ML. Antagonism of a peripheral vascular but not an apparently central serotonergic response by xylamidine and BW 501C67. European Journal of Pharmacology. June 1986, 125 (1): 71–7. PMID 3732393. doi:10.1016/0014-2999(86)90084-1.
- ^ Dedeoğlu A, Fisher LA. Central and peripheral injections of the 5-HT2 agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, modify cardiovascular function through different mechanisms. The Journal of Pharmacology and Experimental Therapeutics. December 1991, 259 (3): 1027–34. PMID 1762059.
- ^ The Wellcome Foundation. Werkwijze voor het bereiden van amidinen of daarvan afgeleide zuur-additiezouten, die werkzaam zijn als antagonisten van 5-hydroxytryptamine, en van farmaceutische preparaten, die ten minste een van deze verbindingen als werkzame verbinding bevatten（荷蘭文）, 1965. NL6508754A.