絨毛膜促性腺激素β亞基

位於19號人類染色體的基因

絨毛膜促性腺激素β亞基(英語:Choriogonadotropin subunit beta,CG-beta,也被稱為絨毛膜促性腺激素,β肽鏈 chorionic gonadotrophin chain beta) 是一個由人類基因CGB 編碼的蛋白質[1][2][3]

Chorionic gonadotropin, beta polypeptide
絨毛膜促性腺激素,β多肽
PDB rendering based on 1hcn.
有效結構
PDB 直系同源檢索:PDBe, RCSB
標識
代號 CGB; CGB3; CGB5; CGB7; CGB8; hCGB
擴展標識 遺傳學118860 同源基因37338 GeneCards: CGB Gene
直系同源體
物種 人類 小鼠
Entrez 1082 n/a
Ensembl ENSG00000104827 n/a
UniProt P01233 n/a
mRNA序列 NM_000737 n/a
蛋白序列 NP_000728 n/a
基因位置 Chr 19:
49.53 – 49.53 Mb
n/a
PubMed查詢 [1] n/a

β肽鏈的145個胺基酸殘基的序列為:

NH2 - Ser - Lys - Glu - Pro - Leu - Arg - Pro - Arg - Cys - Arg - Pro - Ile - Asn - Ala - Thr - Leu - Ala - Val - Glu - Lys - Glu - Gly - Cys - Pro - Val - Cys - Ile - Thr - Val - Asn - Thr - Thr - Ile - Cys - Ala - Gly - Tyr - Cys - Pro - Thr - Met - Thr - Arg - Val - Leu - Gln - Gly - Val - Leu - Pro - Ala - Leu - Pro - Gln - Val - Val - Cys - Asn - Tyr - Arg - Asp - Val - Arg - Phe - Glu - Ser - Ile - Arg - Leu - Pro - Gly - Cys - Pro - Arg - Gly - Val - Asn - Pro - Val - Val - Ser - Tyr - Ala - Val - Ala - Leu - Ser - Cys - Gln - Cys - Ala - Leu - Cys - Arg - Arg - Ser - Thr - Thr - Asp - Cys - Gly - Gly - Pro - Lys - Asp - His - Pro - Leu - Thr - Cys - Asp - Asp - Pro - Arg - Phe - Gln - Asp - Ser - Ser - Ser - Ser - Lys - Ala - Pro - Pro - Pro - Ser - Leu - Pro - Ser - Pro - Ser - Arg - Leu - Pro - Gly - Pro - Ser - Asp - Thr - Pro - Ile - Leu - Pro - Gln - COOH

參考文獻

  1. ^ Entrez Gene: chorionic gonadotropin. 
  2. ^ Fiddes JC, Goodman HM. The cDNA for the beta-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3'-untranslated region. Nature. August 1980, 286 (5774): 684–7. PMID 6774259. doi:10.1038/286684a0. 
  3. ^ Policastro P, Ovitt CE, Hoshina M, Fukuoka H, Boothby MR, Boime I. The beta subunit of human chorionic gonadotropin is encoded by multiple genes. J. Biol. Chem. October 1983, 258 (19): 11492–9. PMID 6194155. 

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