苯並噻二嗪
化合物
苯並噻二嗪是一種雙環雜環苯衍生物，雜環含有兩個氮和一個硫。[1]
| 苯並噻二嗪 | |
|---|---|
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| IUPAC名 2H-1,2,4-Benzothiadiazine | |
| 識別 | |
| CAS號 | 255-18-5 
|
| PubChem | 473368 |
| ChemSpider | 10660057 |
| SMILES |
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| InChI |
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| InChIKey | HAVZTGSQJIEKPI-UHFFFAOYAH |
| 性質 | |
| 化學式 | C7H6N2S |
| 摩爾質量 | 150.2 g·mol−1 |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
一些苯並噻二嗪衍生物可用作藥物，包括：
參考資料
- ^ Hu Z, Martí J, Lu H. Structure of benzothiadiazine at zwitterionic phospholipid cell membranes. The Journal of Chemical Physics. October 2021, 155 (15): 154303. Bibcode:2021JChPh.155o4303H. PMID 34686044. S2CID 239471390. arXiv:2107.14565
. doi:10.1063/5.0065163.
- ^ 2.0 2.1 Hu Z, Marti J. In Silico Drug Design of Benzothiadiazine Derivatives Interacting with Phospholipid Cell Membranes. Membranes. March 2022, 12 (3): 331. PMC 8949146 . PMID 35323806. doi:10.3390/membranes12030331 .
- ^ Huwaimel BI, Bhakta M, Kulkarni CA, Milliken AS, Wang F, Peng A, et al. Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity*. ChemMedChem. April 2021, 16 (7): 1143–1162. PMC 8035258 . PMID 33331124. doi:10.1002/cmdc.202000729.
- ^ Varano F, Catarzi D, Colotta V, Squarcialupi L, Matucci R. 1,2,4-Benzothiadiazine-1,1-dioxide derivatives as ionotropic glutamate receptor ligands: synthesis and structure-activity relationships. Archiv der Pharmazie. November 2014, 347 (11): 777–785. PMID 25204434. S2CID 1765795. doi:10.1002/ardp.201400192.
- ^ Ganeshpurkar A, Gutti G, Singh SK. Chapter 1 - RNA-Dependent RNA Polymerases and Their Emerging Roles in Antiviral Therapy. SP (編). Viral Polymerases. Academic Press. 2019-01-01: 1–42. ISBN 978-0-12-815422-9. S2CID 92095885. doi:10.1016/B978-0-12-815422-9.00001-2 （英語）.
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