黑素皮質素受體
黑素皮質素受體（英語：Melanocortin receptor，縮寫MCR）是七跨膜的G蛋白偶聯受體中視紫質家族的一員，在人類基因組包括五個成員[1]，各自對不同黑素皮質素有不同親和活性[2][3][4]：
參考文獻
- ^ Melanocortins and the Melanocortin Receptor. [2007-03-14]. （原始內容存檔於2007-04-11）.
- ^ Voisey J, Carroll L, van Daal A. Melanocortins and their receptors and antagonists. Current Drug Targets. October 2003, 4 (7): 586–97. PMID 14535656. doi:10.2174/1389450033490858.
- ^ Hadley ME, Dorr RT. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization. Peptides. April 2006, 27 (4): 921–30. PMID 16412534. doi:10.1016/j.peptides.2005.01.029.
- ^ Dores RM. Adrenocorticotropic hormone, melanocyte-stimulating hormone, and the melanocortin receptors: revisiting the work of Robert Schwyzer: a thirty-year retrospective. Annals of the New York Academy of Sciences. April 2009, 1163 (1): 93–100. PMID 19456331. doi:10.1111/j.1749-6632.2009.04434.x.
- ^ Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O'Rahilly S. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N. Engl. J. Med. 2003, 348 (12): 1085–95. PMID 12646665. doi:10.1056/NEJMoa022050.
外部連結
- Melanocortin Receptors. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. [2020-12-16]. （原始內容存檔於2021-01-30）.
- 醫學主題詞表（MeSH）：Melanocortin+Receptors
- Calculated spatial position of melanocortin-4 receptor in the lipid bilayer, inactive state with antagonist （頁面存檔備份，存於網際網路檔案館） and active state with agonist （頁面存檔備份，存於網際網路檔案館）