吉法酯

化合物

吉法酯(英語:Gefarnate,或譯為合歡香葉酯)是一種用於治療胃及十二指腸潰瘍的藥物[1],也可用於治療乾眼症[2][3]

吉法酯
Skeletal formula
Space-filling model
臨床資料
AHFS/Drugs.com國際藥品名稱
ATC碼
識別資訊
  • (2E)-3,7-dimethylocta-2,6-dien-1-yl (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate
CAS號51-77-4  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.000.111 編輯維基數據鏈接
化學資訊
化學式C27H44O2
摩爾質量400.637 g/mol
3D模型(JSmol英語JSmol
  • CC(C)=CCC/C(C)=C/CC/C(C)=C/CCC(=O)OC/C=C(C)/CCC=C(C)C
  • InChI=1S/C27H44O2/c1-22(2)12-8-14-24(5)16-10-17-25(6)18-11-19-27(28)29-21-20-26(7)15-9-13-23(3)4/h12-13,16,18,20H,8-11,14-15,17,19,21H2,1-7H3/b24-16+,25-18+,26-20+ ☒N
  • Key:ZPACYDRSPFRDHO-ROBAGEODSA-N ☒N

參考文獻

  1. ^ Ohta Y, Kobayashi T, Imai Y, Inui K, Yoshino J, Nakazawa S. Effect of gefarnate on acute gastric mucosal lesion progression in rats treated with compound 48/80, a mast cell degranulator, in comparison with that of teprenone. Biol. Pharm. Bull. August 2005, 28 (8): 1424–30 [2019-12-20]. PMID 16079487. doi:10.1248/bpb.28.1424. (原始內容存檔於2019-08-30). 
  2. ^ Peral A, Domínguez-Godínez CO, Carracedo G, Pintor J. Therapeutic targets in dry eye syndrome. Drug News Perspect. April 2008, 21 (3): 166–76. PMID 18560615. 
  3. ^ Gipson IK, Hori Y, Argüeso P. Character of ocular surface mucins and their alteration in dry eye disease. Ocul Surf. April 2004, 2 (2): 131–48 [2019-12-20]. PMID 17216084. doi:10.1016/s1542-0124(12)70149-0. (原始內容存檔於2020-05-20).